Thanks for all the great feedback guys. I really am looking for specifics so any literal alias trigger combos (like Mya, Pali, Dey, Voodoo, and LA offered) would still be tremendously appreciated. Learning proper/efficient input to me seems like a gaming fundamental that might be taken for granted and is in fact, even more important than knowing classes/equip/areas/etc.
It's like trying to play a console game on a controller with only one hand where the vets are using two and expecting to be competitive.
I specifically use a MUD client called JMC. It offers a lot of advanced functionality once you learn how to implement it. For advanced play I look for two things in a client:
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Set aliases, triggers etc from the command line and;
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Set variables.
Before we get into that, First - what's the fastest way to input a command - or more specifically, the least effort to give the MUD a command? A single keystoke. For example - never type 'east' always type 'e'
Following form this - to gain maximum speed advantage you should bind commands to single key strokes as this is the fastest way to input the commands.
*Disclaimer: Always enter a the key you intend to bind a command to first - just because you don't think it does something doesn't mean you're right. An alias will override the key stroke - hence if you bind 'e' to 'drink fountain' you're going to have a very hard time traveling east 
Say you're warrior is fighting L-A in a PK - you probably want to have your command's handy. So, before engaging you do the following:
alias t charge L-A
alias g bash L-A
alias v murder L-A
alias y dirt L-A
Right, now you're one keystroke away from being able to get me with four of your skills. If you can type fast the difference is very little - but that little can add up during a PK chase. The down side is that's a fair bit of typing, you might screw it up with a typo and L-A might see you coming and interrupt you. Still, once you're in combat you're pretty well setup for a good fight and fast chase.
Pro tip: Set up a 'basic set' of aliases for all characters - v for murder (above) is a good one. Everyone can do this and you'll get used to it over time. If you changed to an invoker you might set t, g and y to specific spells instead of warrior skills.
In order to streamline the process I make use of variables. These are expressions that can be assigned different values. For example:
$prey = L-A sets 'prey' to L-A. Hence I can type 'prey' and 'L-A' gets given to the MUD.
How is this useful? Like this:
alias t charge $prey
alias g bash $prey
alias v murder $prey
alias y dirt $prey
By altering the value of the variable 'prey' you can alter who the commands target. To make this every faster I use a single word to set the value of prey to eliminate the $ which takes longer to type:
alias prey %1 {$prey = %1}
If you've done programming you probably can work out what just happened. If not the %1 represents something you enter which is then called again later in the line. In this case if you enter
'prey L-A' the variable 'prey' is assigned the value of 'L-A' This is because in the middle of the PK I don't want to have to worry about typing the $ correctly when I'm more worried about not getting my @$$ kicked.
Hence if you're fighting L-A and Pali rudely interrupts, you can just enter 'prey Pali' and all your commands are automatically reset to your new target - Pali. That's a whole lot less typing and general jerking around while someone is trying to bash your head in.
L-A